CLINICAL AND IN VITRO MODELS IDENTIFY DISTINCT ADAPTATIONS ENHANCING STAPHYLOCOCCUS AUREUS PATHOGENESIS IN HUMAN MACROPHAGES.

Clinical and in vitro models identify distinct adaptations enhancing Staphylococcus aureus pathogenesis in human macrophages.

Staphylococcus aureus is a facultative intracellular pathogen of human macrophages, which facilitates chronic infection.The genotypes, pathways, and mutations influencing that phenotype remain incompletely explored.Here, we hookah parts used two distinct strategies to ascertain S.aureus gene mutations affecting pathogenesis in macrophages.First, we

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Experiences of using the Theoretical Domains Framework across diverse clinical environments: a qualitative study

Cameron J Phillips,1,2 Andrea P Marshall,3,4 Nadia J Chaves,5 Stacey K Jankelowitz,6,7 Ivan B Lin,8 Clement T Loy,9,10 Gwyneth Rees,11 Leanne Sakzewski,12 Susie Thomas,13,14 The-Phung To,15 Shelley A Wilkinson,16,17 Susan Michie18 1Division of Pharmacy, Flinders Medical Centre, Bedford Park, SA, Australia; 2School of Medicine, Flinders University,

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