Clinical and in vitro models identify distinct adaptations enhancing Staphylococcus aureus pathogenesis in human macrophages.
Staphylococcus aureus is a facultative intracellular pathogen of human macrophages, which facilitates chronic infection.The genotypes, pathways, and mutations influencing that phenotype remain incompletely explored.Here, we hookah parts used two distinct strategies to ascertain S.aureus gene mutations affecting pathogenesis in macrophages.First, we